GATAD2B Antikörper (N-Term)

Produktnummer ABIN2781110

Dieser Anti-GATAD2B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von GATAD2B in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für GATAD2B Antikörper (N-Term) (ABIN2781110)

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GATAD2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GATAD2B Antikörper

Bindungsspezifität: N-Term

Sequenz: MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GATAD2B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GATAD2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 593 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GATAD2B

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Andere Bezeichnung: GATAD2B

Hintergrund: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.
Alias Symbols: P66beta, RP11-216N14.6
Protein Interaction Partner: USHBP1, CEP70, RPGRIP1, TEX11, MBD3, TRIM27, PRKAB2, GOLGA2, CALCOCO2, TRAF1, SUMO2, UBC, ZBTB1, SUZ12, EED, RNF2, HDAC2, HDAC1, SMAD2, MTA3, NOTCH1, MTA2, MTA1, NDUFA7, NDUFA2, SOX2, PARK7, tat, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, RBBP7, RBBP4, Fox
Protein Size: 593

Molekulargewicht: 65 kDa

Gen-ID: 57459

NCBI Accession: NM_020699, NP_065750

UniProt: Q8WXI9